Endocrine Abstracts

The aim of our study was to assess the influence of radioiodine (131I) therapy on the achievement of euthyroidism, prevention of adverse effects on the cardiovascular and prevent evolvement to overt hyperthyroidism.Materials and methods: We treated 1600 patients refered to our department during the last 8 years, aged 23–77 years; 89% of them were females and 11% males; 520 patients with multinodular goitre (MNG), and 1080 patients with au...

Objectives: Patients with thyroid dysfunction due to AITD have been found to have increased oxidative stress. Possible associations of oxidative stress with thyroid hormone (TH) and thyroid autoantibodies (ThAb) levels in euthyroid patients with autoimmune thyroiditis have not been adequately studied. We examined possible associations of oxidative stress markers with TH levels and with the presence of ThAb in euthyroid women with Hashimoto’s thyroiditis (with or without T...

Introduction: Glycemic variability (GV) has been associated, regardless to A1C levels, to chronic complications of diabetes mellitus (DM).Objective: To describe baseline characteristics, GV parameters, and microvascular complications rates in a selected simple of type 1 diabetes patients (T1DM) on continuous subcutaneous insulin infusion (CSII).Methods: We performed a retrospective observational study with 130 T1DM patientson (CSII...

Introduction: Typical and atypical bronchial carcinoids (TBC and ABC) are well-differentiated neuroendocrine neoplasms (NEN). First-line treatment is radical removal of the primary tumour; however, management of metastatic BC is still challenging. Bronchial carcinoids (BC) may benefit from treatment with mTOR inhibitors, although response rates are moderate. TBC have shown reduced sensibility to mTOR inhibitors respect to ABC, notwithstanding its less aggressive behaviour. PI3...

Aim: Current guidelines for type 1 diabetes mellitus (DM1) suggest a therapeutic goal for glycosylated hemoglobin (A1c) of < 7.0% in adults and < 7.5% in children and adolescents, while emphasizing the importance of managing dyslipidemia. We aimed to record the achievement of therapeutic goals in DM1 patients followed-up in a Greek tertiary center.Methods: Data were included from DM1 patients who had visited the Department at least once in the pr...

Background: Community acquired pneumonia (CAP) is a common condition and a major cause of morbidity. Diabetes mellitus (DM) increases the risk and complications of infectious diseases. However, it is necessary to clarify if DM and glycemia at the time of presentation are prognostic factors in patients with CAP.Objectives: To evaluate the relationship between DM/glycemia at the time of presentation and complications, length of stay and mortality in patien...

Background and aims: Periodontal disease (PD) is a chronic inflammatory condition where the key feature is the alveolar bone loss. Diabetes mellitus is a major risk factor in the occurrence of PD and vitamin D has been found to play a role in the development of diseases such as PD for its immunomoduratory and anti-inflammatory effects. The purpose of this study was to evaluate the relationship between PD and vitamin D levels in type 1 diabetic patients.S...

Bilateral cervical exploration has been the gold standard in parathyroid surgery. Nowadays, the preoperative localization procedures have facilitated the minimally invasive surgery. This study aims to analyze the influence of thyroid disease in Tc99m-sestamibi scintigraphy (MIBI) results.A series of 154 patients with PHP who underwent parathyroidectomy was reviewed. Patients were divided into two groups: group 1 (G1, 58 patients) with thyroid diseases, a...

Background: Primary aldosteronism is a common cause of arterial hypertension, but its underlying molecular mechanisms are unknown. K+ is a key regulator of aldosterone secretion: it interacts with physiological secretagogues of aldosterone as angiotensin II (Ang II) end endothelin-1. In vivo genetic manipulation of a widely distributed class of channels, which generate background or ‘leak’ potassium (K+) currents, the twik-related acid-se...

Objective: To identify MetS and non-MetS in subjects with adult-onset GHD before start of GH replacement and to compare prevalence of cardiovascular risk factors.Subjects and methods: MetS was defined (IDF criteria) by the obligatory presence of increased waist circumference (WC) and presence of at least two of following components: hypertension, decreased HDL-cholesterol, increased triglycerides, diabetes mellitus. The complementary group was defined as...